Perhaps nothing is more anxiety-provoking for a woman than to be told she has a breast mass or an abnormal mammogram and should have a biopsy. Breast pathology encompasses examination of core biopsy, lumpectomy, and mastectomy specimens from patients, and cytopathologic examination of needle aspirate specimens is performed in our laboratory as well. We carefully examine each specimen for evidence of pre-cancers and cancers as well as benign lesions that would explain abnormal clinical findings. When a cancer is diagnosed we evaluate many parameters including tumor grade and, if applicable, tumor stage and margin status. Estrogen receptor, progesterone receptor, and HER2/neu immunohistochemical stains are promptly performed in our laboratory on carcinomas to quickly yet accurately provide surgeons and oncologists with additional information that is important in determining the best treatment options for each individual patient. In addition, we interpret HER2/neu fluorescence in-situ hybridization (FISH) studies and can, upon request, refer your biopsy for additional specialized testing such as OncotypeDx.